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Conclusion Cu(II)-binding affinities for three major blood copper proteins: human serum albumin, ceruloplasmin and alpha-2-macroglobulin, were studied through their competition with a set of low-molecular weight Cu(II)-binding reference ligands (DTPA, EDTA, NTA, His) by using an unified LC-ICP MS-based approach

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The skin is chronically exposed to both endogenous and environmental pro-oxidants leading to the production of ROS.[] ROS leads to lipid peroxidation, which is considered as the hallmark of oxidative stress in body.[] Malondialdehyde (MDA) is considered as the end product of lipid peroxidation and MDA levels is directly proportional to the oxidative stress.[] The most important antioxidants present in human body include superoxide dismutase, glutathione peroxidase, and catalase.[] Glutathione which is considered a master antioxidant can help keep the balance between the oxidant and antioxidant system in the body and prove to be an effective therapy but studies proving its efficacy are limited

& Veldhuis, J